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mammary cells

USP5 Promotes Breast Cancer Cell Proliferation and Metastasis by Stabilizing HIF2α

[Journal of Cellular Physiology] Ubiquitin-specific peptidase 5 (USP5) stabilized hypoxia-inducible factor 2α (HIF2α) through its deubiquitinase activity and provided a potential therapeutic target for breast cancer.

Hypoxia-Induced lncRNA RBM5-AS1 Promotes Tumorigenesis via Activating Wnt/β-Catenin Signaling in Breast Cancer

[Cell Death & Disease] Overexpression of RBM5-AS1 facilitated proliferation, migration, invasion, EMT, and stemness maintenance of breast cancer cells in vitro and in vivo.

Structural and Morphological Changes of Breast Cancer Cells Induced by Iron(II) Complexes

[Nanoscale] The authors characterized the effects of iron(II)-based complexes on the structural and morphological properties of epithelial non-tumorigenic and tumorigenic breast cell lines using atomic force microscopy, flow cytometry and immunofluorescence microscopy.

Engineer a Pre-Metastatic Niched Microenvironment to Attract Breast Cancer Cells by Utilizing a 3D Printed Polycaprolactone/Nano-Hydroxyapatite Osteogenic Scaffold – an In Vitro Model System...

[Journal of Biomedical Materials Research Part B-Applied Biomaterials] A transwell migration assay was used to investigate recruitment of MDA-MB-231, MCF-7, and MDA-MB-453 breast cancer cells to the osseous polycaprolactone-nano-hydroxyapatite scaffolds.

DNMT1 Facilitates Growth of Breast Cancer by Inducing MEG3 Hyper-Methylation

[Cancer Cell International] Investigators demonstrated that, DNMT1 induced methylation of MEG3 promoter, and played a key role in breast cancer growth throughmiR-494-3p/OTUD4 axis.

Ultrasound Targeted Microbubble Destruction-Mediated SOCS3 Attenuates Biological Characteristics and Epithelial-Mesenchymal Transition (EMT) of Breast Cancer Stem Cells

[Bioengineered] The authors explored the effects of ultrasound targeted microbubble destruction -mediated transfection of SOCS3 on the biological characteristics and EMT of breast cancer stem cells.

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