mammary cells

[Molecular Therapy-Nucleic Acids] The authors reported DGUOK-AS1 overexpression promoted breast cancer cell migration, angiogenesis, and macrophage migration, mediated by the increased secretion of IL11, which was extremely important for cancer progression.

[Cell Death & Disease] The authors showed that TRIM31 was downregulated in breast cancer tissues and negatively correlated with breast cancer progression. Both gain- and loss-of-function assays indicated that TRIM31 inhibited the proliferation, colony formation, migration, and invasion of breast cancer cells.

[Breast Cancer Research] Researchers showed that fluid forces on the order of 1 Pa promoted epithelial-to-mesenchymal transition and adhesion of breast cancer cells to an endothelial monolayer and identified biomarkers were distinctly expressed in patient populations.

[Breast Cancer Research] Scientists investigated the effect of oestrogen deprivation on the expression of chemokines and immune infiltration in vitro and in an ER+ immunocompetent mouse model.

[Journal of Cell Science] Researchers reported the identification of 114 novel long non-coding RNAs that changed their expression during TGFβ-induced epithelial-mesenchymal transition in murine breast cancer cells.

[Cell Death & Disease] The authors identified MINDY1, a member belongs to the motif interacting with Ubcontaining novel DUB family (MINDY), as a potential deubiquitylase of estrogen receptor α in breast cancer.