mesenchymal stem cells

[Pharmacology & Therapeutics] The authors discuss the production of antimicrobial peptides by MSCs, revise the multiple functions of these peptides, including their influence over MSCs, and present an overview of clinical situations in which the antimicrobial properties of MSCs may be explored for therapy.

[Bone Marrow Transplantation] Investigators provide an overview of the cellular therapies available for the management of systemic sclerosis, including systemically injected therapies and locally administered regenerative cell therapies.

[Colloids and Surfaces B-Biointerfaces] Injectable GO/laponite/gelatin (GO-LG) hydrogel was developed and characterized. The results of cell viability showed that the optimal concentration of GO flasks to treat cells was 100 μg/ml.

[International Immunopharmacology] Scientists investigated the anti-inflammatory properties of small extracellular vesicles derived from human umbilical cord MSCs in a diabetic rat model and human retinal microvascular endothelial cells.

[European Respiratory Journal] Scientists comparatively assessed how the inflammatory environment present in acute respiratory distress syndrome lungs versus the lung environment present in healthy volunteers alters MSC behavior.

[Journal of Molecular Histology] The authors investigated whether stromal cell-derived factor (SDF)-1 secreted by mesenchymal stem cells contributed to endothelial progenitor cell migration to ischemic sites via CXCR4/Phosphoinositide 3-Kinases/protein kinase B signaling pathway.