mesenchymal stem cells

[EV Biologics Corp. (BioSpace)] EV Biologics Corp. announced that it has signed a Letter of Intent (LOI) with Lonza Cell & Gene Therapy for Process Development and Gap Analysis for biomanufacturing of a novel therapeutic composition, comprising extracellular vesicles and particles, as well as other secreted factors derived from selected stem/progenitor cells, such as MSCs.

[Scientific Reports] Scientists presented an integrative analysis of clinical data, cytokines, serum metabolomics in rheumatoid arthritis patients and mechanistic studies on adenosine deaminase-mediated effects on in vitro cell culture models.

[Heliyon] Researchers demonstrated the feasibility of bone marrow MSCs harvested from forearm bone marrow with small volume samples.

[Cell Biology International] Cardiac function, myocardial infarction area, apoptosis, and angiogenesis were all evaluated in a CHF rat model following treatment with human umbilical cord MSC-derived exosomes.

[Scientific Reports] The authors investigated the beneficial effects of exosomes derived from bone marrow MSCs on trabecular meshwork cells under oxidative stress and predicted candidate genes associated with this process.

[Molecular Therapy-Nucleic Acids] A new strategy to modify MSCs to express specific chemokine receptors using mRNA engineering was developed to evaluate the homing ability of MSCs and its therapeutic effects for inflammatory bowel disease.