microglia

[Acta Pharmacologica Sinica] Researchers showed that sulforaphane confered stress resilience via brain-derived neurotrophic factor upregulation and changes in abnormal dendritic spine morphology in stressed mice, which was accompanied by rectifying the irregular levels of inflammatory cytokines.

[mBio] The authors review the current achievements in brain organoid biology and their relevance to HIV infection of the brain (neuroHIV) research efforts.

[Nature] Astrocytes produced IL-3, which elicited transcriptional, morphological, and functional programming of microglia to endow them with an acute immune response program, enhanced motility, and the capacity to cluster and clear aggregates of Aβ and tau.

[Scientific Reports] Scientists used a RiboTag strategy to characterize ribosome-bound mRNA only in microglia without incurring possible transcriptional changes after cell isolation.

[Cell] Investigators showed that GABA-receptive microglia selectively interacted with inhibitory cortical synapses during a critical window of mouse postnatal development.

[Journal of Enzyme inhibition and Medicinal Chemistry] A new generation of carbonic anhydrase inhibitors and acetazolamide were investigated in two models of brain ischaemia: in rat hippocampal acute slices exposed to severe oxygen, glucose deprivation and in an in vivo model of focal cerebral ischaemia induced by permanent occlusion of the middle cerebral artery in the rat.