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muscle cells
Muscle Cell News
microRNA-124-3p Attenuates Myocardial Injury in Sepsis via Modulating SP1/HDAC4/HIF-1α Axis
[Cell Death Discovery] Septic rats were modeled by cecal ligation puncture while in vitro septic cardiomyocyte H9C2 were induced by lipopolysaccharide.
Muscle Cell News
LncRNA XR_596701 Protects H9c2 Cells against Intermittent Hypoxia-Induced Injury through Regulation of the miR-344b-5p/FAIM3 Axis
[Cell Death Discovery] Gene expressions of XR_596701 and miR-344b-5p were detected by quantitative real-time polymerase chain reaction in intermittent hypoxia-induced H9c2 cells.
Muscle Cell News
Cardiomyocyte IL-1R2 Protects Heart from Ischemia/Reperfusion Injury by Attenuating IL-17RA-Mediated Cardiomyocyte Apoptosis
[Cell Death & Disease] After myocardial ischemia reperfusion surgery, IL-1R2 expression was significantly increased in heart of wild-type mice.
Muscle Cell News
Mechanism of miR-378a-3p Enriched in M2 Macrophage-Derived Extracellular Vesicles in Cardiomyocyte Pyroptosis after MI
[Hypertension Research] An in vitro cell model was established, followed by a comprehensive evaluation of cell viability and pyroptosis. The binding relationships of miR-378a-3p and ELAVL1, HuR, and NLR family pyrin domain containing 3 were analyzed.
Muscle Cell News
Microskeletal Stiffness Promotes Aortic Aneurysm by Sustaining Pathological Vascular Smooth Muscle Cell Mechanosensation via Piezo1
[Nature Communications] Scientists showed defective mechano-phenotype signatures of vascular smooth muscle cells in abdominal aortic aneurysms measured with ultrasound tweezers-based micromechanical system and single-cell RNA sequencing technique.
Muscle Cell News
Intrinsic Cardiac Adrenergic Cells Contribute to LPS-Induced Myocardial Dysfunction
[Communications Biology] Researchers showed that norepinephrine secretion from intrinsic cardiac adrenergic cells was increased through activation of Toll-like receptor 4 to aggravate myocardial TNF-α production and dysfunction by lipopolysaccharide (LPS).