myeloid cells

[International Journal of Stem Cells] The protein expression of AKT, mTOR, p-AKT and p-mTOR was detected using western blot assay. The results showed that human umbilical cord mesenchymal stem cells treatment prominently promoted the glucocorticoid-induced the decrease of the collagen level and the increase of TRAP positive cells.

[American Journal of Hematology] Researchers evaluated 7861 patients with hematologic malignancies who received either a cord blood transplantr without anti-thymocyte globulin (ATG) or an HLA 1-3 antigen–mismatched related donor peripheral blood stem-cell transplantation using low-dose ATG.

[Cell] Researchers identified highly activated, CD16+ T cells with increased cytotoxic functions in severe COVID-19.

[Proceedings of the National Academy of Sciences of the United States of America] A strong response was induced in monocytes and B cells, with a SARS-CoV-2–specific inflammatory gene cluster distinct from that seen in influenza A or Ebola virus-infected cocultures, and which reproduced deviations reported in blood or lung myeloid cells from COVID-19 patients.

[Cellular & Molecular Immunology] The authors provided evidence to support the function of KLF14, a novel Krüppel-like transcription factor, in the regulation of glycolysis and the immune function of macrophages during sepsis.

[Cellular & Molecular Immunology] Investigators showed that ACE2-overexpressing A549 cell-derived microparticles were a potential therapeutic agent against SARS-CoV-2 infection.