myocytes

[Nature Communications] Treatment of Chkb−/− myocytes with peroxisome proliferator-activated receptor agonists enabled fatty acids to be used for β-oxidation and prevented triacyglyerol accumulation, while simultaneously increasing expression of the compensatory choline kinase alpha isoform, preventing muscle cell injury.

[Molecular Therapy] Researchers reported that cardiac stress-induced differential microRNA content, with miR-200c-3p being one of the most enriched, in cardiomyocyte-derived extracellular vesicles mediates functional crosstalk with endothelial cells.

[Bmb Reports] Scientists investigated whether tactical control of muscleblind-like 1 (MBNL1) activity could alter myofibroblast activity and fibrotic outcomes.

[Cell Death & Disease] After myocardial ischemia reperfusion surgery, IL-1R2 expression was significantly increased in heart of wild-type mice.

[Laboratory Investigation] Researchers revealed that hypoxia/reoxygenation (H/R) treated human cardiac myocytes showed a significantly decreased miR-185-5p expression and increased expression of CDK6 and ROR.

[Scientific Reports] Scientists performed fully-mismatched heart transplantations and found combination treatment to result in prolonged allograft survival.