Tag results:
myocytes
Muscle Cell News
Control of Satellite Cell Function in Muscle Regeneration and Its Disruption in Aging
[Nature Reviews Molecular Cell Biology] Skeletal muscle contains a designated population of adult stem cells, called satellite cells, which are generally quiescent. The authors discuss the role and regulation of satellite cells in skeletal muscle homeostasis and regeneration.
Extracellular Matrix News
Collagen-Derived Dipeptide Pro-Hyp Administration Accelerates Muscle Regenerative Healing Accompanied by Less Scarring after Wounding on the Abdominal Wall in Mice
[Scientific Reports] Pro-Hyp administration induced many myogenically differentiated cells, including myogenin-positive myoblasts and myoglobin-positive myocytes, to migrate in the granulation tissue, while scar tissue decreased, indicating that Pro-Hyp administration accelerated muscle regenerative healing accompanied by less scarring after wounding on the abdominal wall.
Extracellular Matrix News
Hemicentin-1 Is an Essential Extracellular Matrix Component of the Dermal–Epidermal and Myotendinous Junctions
[Scientific Reports] Performing in situ hybridization and immunofluorescence analysis, researchers found that mouse Hmcn1 and Hmcn2 showed a complementary distribution throughout different tissues and developmental stages.
Muscle Cell News
The Hippo Pathway Regulates Density-Dependent Proliferation of iPSC-Derived Cardiac Myocytes
[Scientific Reports] The Hippo pathway regulates the proliferation of cancer cells, pluripotent stem cells, and epithelial cells through a cell–cell contact-dependent manner, however, it is unclear if cell density-dependent cell proliferation is a consistent feature in cardiac myocytes. Scientists used cultured human iPSC-derived cardiac myocytes as a model system to investigate this concept.
Hepatic Cell News
Hepatocyte-Derived Exosomes from Early Onset Obese Mice Promote Insulin Sensitivity through miR-3075
[Nature Metabolism] FA2H was a direct target of miR-3075 and small interfering RNA depletion of FA2H in adipocytes, myocytes and primary hepatocytes led to increased insulin sensitivity. In chronic obesity, hepatocyte exosomes promoted a state of insulin resistance.
Extracellular Matrix News
Tissue-Engineered Esophagus: Recellular Esophageal Extracellular Matrix Based on Perfusion-Decellularized Technique and Mesenchymal Stem Cells
[Biomedical Materials] In this study, the esophageal extracellular matrix scaffold was successfully constructed by perfusion-decellularized technique through the vascular system for the first time.