myocytes

[Scientific Reports] Researchers investigated how ICG001 could prevent cardiac hypertrophy and fibrosis induced by transverse aortic constriction and found it may have mediated the substrates in the glycolysis pathway and the distinct alteration of oxidative stress during cardiac hypertrophy and heart failure.

[Scientific Reports] Manipulation of cultured cardiomyocytes toward homogeneously aligned increased their contractility, suggesting that homogeneous alignment in dilated cardiomyopathy mice was due to a sort of alignment remodelling as a way to compensate cardiac dysfunction.

[Seminars in Cell & Developmental Biology] In recent years, direct reprogramming of resident cardiac fibroblasts to induced cardiac-like myocytes has emerged as a promising therapeutic strategy to repurpose the fibrotic response of the injured heart toward a functional myocardium.

[Scientific Reports] Investigators determined the effect of cell type-specific deletion of protease-activated receptor 1 (PAR1) in cardiac myocytes and cardiac fibroblasts on Coxsackievirus B3-induced myocarditis.

[Pflugers Archiv-European Journal of Physiology] Scientists investigated the contribution of the tissue-specific erythropoietin (EPO)-receptor (EpoR) to exercise-induced remodeling of cardiac and skeletal muscle and indicated that the endogenous EPO-EpoR system controlled mitochondrial biogenesis in skeletal muscle.

[Scientific Reports] In an in vitro model of myogenesis, the expression of nTRIP6 was transiently up-regulated at the transition between proliferation and differentiation, whereas that of the cytosolic isoform TRIP6 was not altered.