neural cells

[Accelerated Biosciences (BusinessWire, Inc.)] Accelerated Biosciences announced new data that further demonstrates statistically significant cytolysis with iPSc-derived natural killer cells programmed from its ethically sourced hTSCs.

[Nature Neuroscience] We sought potential drivers of this selective vulnerability using single-nucleus RNA sequencing and discovered that ApoE expression level is a substantial driver of neuronal variability.

[Nature Neuroscience] Researchers determined the expression of cadherins and cell-type markers in 29,933 cells and the projections of 3,164 cells in both the mouse motor cortex and auditory cortex.

[Molecular Psychiatry] Scientists identified functional network parameters that are most reliably affected by GABAergic modulation as such, and through alterations of excitation/inhibition balance by reduced expression of Cadherin - 13 in GABAergic neurons.

[Nature Communications] Investigators have identified 30 affected individuals from 22 unrelated families presenting with developmental delay, hypotonia, and cerebellar ataxia harboring biallelic variants in the GEMIN5 gene.

[Nature Communications] Scientists generated human induced pluripotent stem cell (hiPSC) lines from a patient with Tuberous Sclerosis Complex (TSC) and genetically engineer counterparts and isogenic controls. By differentiating hiPSCs, we show that control neurons respond to canonical guidance cues as predicted.