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neural stem cells

HDL Biodistribution and Brain Receptors in Zebrafish, Using HDLs as Vectors for Targeting Endothelial Cells and Neural Progenitors

[Scientific Reports] Scarb1 gene expression was detected in neural stem cells (NSCs), suggesting a possible role of high density lipoproteins (HDLs) in NSC activity.

Single-Cell Atlas of Early Human Brain Development Highlights Heterogeneity of Human Neuroepithelial Cells and Early Radial Glia

[Nature Neuroscience] Scientists found that organoid systems display low fidelity to neuroepithelial and early radial glia cell types, but improve as neurogenesis progresses.

BASP1 Labels Neural Stem Cells in the Neurogenic Niches of Mammalian Brain

[Scientific Reports] Researchers describe the expression of brain abundant, membrane-attached signal protein 1 (BASP1), in neural stem cells (NSCs) in the developing and postnatal mammalian brains and human brain organoids, and demonstrated that the NSC-6 antibody may be a useful marker of these cells.

Exon Junction Complex Dependent mRNA Localization Is Linked to Centrosome Organization during Ciliogenesis

[Nature Communications] The authors report that exon junction complexes accumulated at basal bodies of mouse neural stem cell or retinal pigment epithelial cells and declined when these cells differentiated or resumed growth.

Formation and Integration of New Neurons in the Adult Hippocampus

[Nature Reviews Neuroscience] Scientists review current knowledge of how levels of neurogenesis are regulated, discuss findings regarding survival and maturation of adult-born cells and describe how newborn neurons affect brain function.

Declining Lamin B1 Expression Mediates Age-Dependent Decreases of Hippocampal Stem Cell Activity

[Cell Stem Cell] Researchers showed that the nuclear lamina protein lamin B1 (LB1) was downregulated with age in mouse hippocampal neural stem cells, whereas protein levels of SUN-domain containing protein 1, previously implicated in Hutchinson-Gilford progeria syndrome, increased.

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