organoids

[Journal of Biological Chemistry] Investigators summarized the different ionization methods, sample preparation steps and data analysis methods of mass spectrometry imaging (MSI) and focuses on several of the latest applications of matrix-assisted laser desorption/ionization MSI for drug studies in spheroids and organoids.

[Journal of Molecular Biology] Scientists discuss state-of-the-art lung, liver and kidney 3D organoid system utilizing the AOPs to study SARS-CoV-2 molecular pathogenesis.

[Korea Biomedical Review] KangStem Biotech said that it has signed a deal with Seoul National University’s R&DB Foundation to receive the university’s skin organoid manufacturing technology.

[Tissue and Cell] A 3D thermo-reversible gelation polymer culture system was established for organoid culture of mouse fallopian tube epithelial stem cells without cell isolation.

[Cell] Looking back, investigators discuss the key developments of this emerging technology. Thinking forward, they focus on the challenges faced to fully establish, validate, and utilize the fidelity of these models for biological research.

[Nature Communications] Investigators utilized forebrain organoids generated from induced pluripotent stem cells of patients with a syndromic form of Autism Spectrum Disorder with a homozygous protein-truncating mutation in CNTNAP2, to study its effects on embryonic cortical development.