Tag results:
pancreatic cells
Pancreatic Cell News
Cadmium Exposure Suppresses Insulin Secretion through mtROS-Mediated Mitochondrial Dysfunction and Inflammatory Response in Pancreatic Beta Cells
[Journal of Trace Elements in Medicine and Biology] Scientists used an in vitro MIN6 cell model of environment-relevant cadmium exposure to elucidate the crucial role of mtROS-mediated mitochondrial dysfunction and inflammatory response in suppression of pancreatic β-cell insulin secretion.
Pancreatic Cell News
Excess Fatty Acids Induce Pancreatic Acinar Cell Pyroptosis through Macrophage M1 Polarization
[BMC Gastroenterology] Scientists found that palmitic acid stimulation led to M1 polarization of macrophage, which secreted cathepsin S via exosomes to pancreatic acinar cells and led to activation of the caspase1-mediated classical pyrolysis pathway.
Pancreatic Cell News
Circ_0072008, an Oncogene in Pancreatic Ductal Adenocarcinoma, Contributes to Tumour Cell Malignant Progression and Glycolysis by Regulating miR-545-3p/SLC7A11 Axis
[Autoimmunity] Expression of circ_0072088, microRNA (miR)-545-3p and solute carrier family 7 member 11 (SLC7A11) was detected by real-time quantitative PCR and western blotting.
Pancreatic Cell News
A Comparison of 64Cu-Labeled Bi-terminally PEGylated A20FMDV2 Peptides Targeting Integrin ανβ6
[Oncotarget] Researchers described the radiolabeling, in vitro and in vivo evaluation of a bi-terminally PEGylated A20FMDV2 conjugated with DOTA or PCTA for 64Cu radiolabeling.
Pancreatic Cell News
Clinical Significance of Pancreatic Ductal Metaplasia
[Journal of Pathology] Pancreatic ductal metaplasia (PDM) development might involve all cell lineages of the pancreas, and acinar cells with the highest plasticity are the major source of PDM.
Pancreatic Cell News
A Two-Phase Approach to Fusicoccane Synthesis to Uncover a Compound That Reduces Tumourigenesis in Pancreatic Cancer Cells
[Angewandte Chemie-International Edition] Scientists generated 15 g of the tricyclic intermediate in 8 steps from ( R )-limonene and 720 mg of the penultimate bioactive intermediate in a protecting-group-free manner.