Tag results:
pancreatic cells
Cell Therapy News
Implanted Pluripotent Stem-Cell-Derived Pancreatic Endoderm Cells Secrete Glucose-Responsive C-peptide in Patients with Type 1 Diabetes
[Cell Stem Cell] The authors reported an analysis on one year of data from the first cohort of 15 patients from a single trial site that received subcutaneous implantation of cell products combined with an immunosuppressive regimen.
Umbilical & Placental Cell News
Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Carrying Hsa-miRNA-128-3p Suppress Pancreatic Ductal Cell Carcinoma by Inhibiting Galectin-3
[Clinical and Translational Oncology] Researchers investigated the effects of exosomes extracted from human umbilical cord mesenchymal stem cells carrying hsa-miRNA-128-3p on pancreatic cancer cells.
Pancreatic Cell News
In Vivo Bioengineering of Beta Cells with Immune Checkpoint Ligand as a Treatment for Early-Onset Type 1 Diabetes Mellitus
[ACS Nano] Investigators described a strategy that utilizes pretargeting and glycochemistry to bioengineer β cells in situ to induce β-cell-specific tolerance.
Pancreatic Cell News
Type IIB PKA Is Highly Expressed in β Cells and Controls Cell Proliferation via Regulating Cyclin D1 Expression
[FEBS Journal] Investigators found that the RIIB subunit of protein kinase A is expressed specifically by β cells of mouse and human islets.
Pancreatic Cell News
CHK1 Protects Oncogenic KRAS-Expressing Cells from DNA Damage and Is a Target for Pancreatic Cancer Treatment
[Cell Reports] Pharmacologic inhibition of CHK1 alone caused apoptotic growth suppression of both PDAC cell lines and organoids, which correlated with loss of MYC expression.
Pancreatic Cell News
Aldo-Ketoreductase 1c19 Ablation Does Not Affect Insulin Secretion in Murine Islets
[PLoS One] Investigators showed that Akr1c19 expression was dramatically decreased in db/db islets.