pancreatic cells

[Current Diabetes Reports] Investigators focus on the recent development of new clinically validated and novel biomarkers as well as the methods that represent cost-effective alternatives for screening and early diagnosis of type 2 diabetes mellitus.

[Journal of Genetics and Genomics] The authors summarize the roles and underlying mechanisms of transcription factors in the maintenance of β-cell identity under physiological and type 2 diabetic conditions.

[Nature Medicine] Porcine and human stem cell-beta islets made insulin in xenotransplant models, and mouse islets tested in a marginal mass syngeneic transplant model cured diabetes in 92% of recipients within 24–48 hours after transplant.

[Scientific Reports] Researchers described that weaning rats fed diets rich in Maillard reaction products were affected in both their immune and endocrine systems.

[Bioscience Reports] Scientists showed that alanine serine cysteine‑preferring transporter 2 (ASCT2) expression was significantly higher in pancreatic cancer than in normal pancreatic duct cells and pancreas.

[Molecular Metabolism] Scientists utilized sorting of physically interacting cells with single-cell RNA-sequencing to systematically map cellular interactions in the endocrine pancreas after pancreatectomy.