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prostate cancer cells

ZBTB38 Suppresses Prostate Cancer Cell Proliferation and Migration via Directly Promoting DKK1 Expression

[Cell Death & Disease] Researchers showed that tumor suppressor ZBTB38 suppressed the migration and proliferation of prostate cancer cells, and found lower ZBTB38 expression in prostate cancer tissues, which predicted a poorer prognosis of prostate cancer.

Moracin D Induces Apoptosis in Prostate Cancer Cells via Activation of PPAR Gamma/PKC Delta and Inhibition of PKC Alpha

[Phytotherapy Research] Researchers explored the apoptotic mechanism of Moracin D in prostate cancer cells in association with peroxisome proliferator-activated receptor gamma (PPAR-γ)-related signaling involved in lipid metabolism.

CKB Inhibits Epithelial-Mesenchymal Transition and Prostate Cancer Progression by Sequestering and Inhibiting AKT Activation

[Neoplasia] Scientists discovered that brain-type creatine kinase (CKB) was a negative regulator of epithelial-mesenchymal transition and AKT activation, which revealed a new mode of their regulation.

Glycoforms of Human Prostate-Specific Membrane Antigen (PSMA) in Human Cells and Prostate Tissue

[Prostate] The authors used mass spectrometry and analyzed the distribution of the site-specific glycoforms of prostate-specific membrane antigens in insect, human embryonic kidney, and prostate cancer cells, and in prostate tissue upon immunoaffinity enrichment.

RANBP10 Promotes Glioblastoma Progression by Regulating the FBXW7/C-Myc Pathway

[Cell Death & Disease] Scientists found that RAN binding protein 10 (RANBP10) was overexpressed in glioblastoma (GBM), and high RANBP10 expression was closely linked to poor survival of patients with GBM.

Bortezomib Potentiates Antitumor Activity of Mitoxantrone through Dampening Wnt/β-Catenin Signal Pathway in Prostate Cancer Cells

[BMC Cancer] Researchers determined the anticancer effects of a combination of bortezomib and mitoxantrone by apoptosis and proliferation assay in vivo and in vitro.

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