prostate cancer cells

[Prostate] Scientists investigated a possible role for protease-activated receptor-2 in regulating the behavior of bone cells exposed to metastatic prostate cancer cells.

[Biophysical Journal] Investigators noted that circulating tumor cells isolated from prostate cancer patients displayed a specific mechanical phenotype, determined with atomic force microscopy: high softness and high adhesion.

[Prostate Cancer and Prostatic Diseases] Researchers examined myokine levels of serum acquired from metastatic CRPC patients recruited to the INTERVAL-GAP4 trial before and after six months of exercise and its tumour-suppressive effect.

[Biophysical Journal] The authors showed that circulating tumor cells isolated from the blood of prostate cancer patients displayed specific nanomechanical phenotypes characteristic of cell endurance and invasiveness and patient sensitivity to androgen deprivation therapy.

[Cancer Research] Researchers described a mechanism by which CAF-secreted lactate was able to increase the expression of genes involved in lipid metabolism in prostate cancer cells.

[Cancer Prevention Research] The authors demonstrated that δ-tocotrienol effectively inhibited the development of prostate adenocarcinoma in Ptenp-/- mice, which involved inhibition of proliferation and angiogenesis and promotion of apoptosis.