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prostate cancer

The Role of Genetic Testing in Prostate Cancer Screening, Diagnosis, and Treatment

[Current Opinion in Oncology] The authors provide an overview of the current role of genetic testing in prostate cancer screening, diagnosis, and treatment.

Boric Acid Suppresses Cell Proliferation by TNF Signaling Pathway Mediated Apoptosis in SW-480 Human Colon Cancer Line

[Journal of Trace Elements in Medicine and Biology] Scientists investigated whether boric acid could be a new candidate molecule that could be used in the treatment of colon cancer.

ERK1/2 Inhibits Cullin 3/SPOP-Mediated PrLZ Ubiquitination and Degradation to Modulate Prostate Cancer Progression

[Cell Death & Differentiation] Researchers reported that prostate leucine zipper (PrLZ) could be degraded by SPOP. PrLZ abundance was elevated in SPOP-mutant expressing prostate cancer cell lines and patient specimens.

A Genome-Scale CRISPR Screen Reveals PRMT1 as a Critical Regulator of Androgen Receptor Signaling in Prostate Cancer

[Cell Reports] Via genome-scale CRISPR-Cas9 screening, scientists identified protein arginine methyltransferase 1 (PRMT1) as a critical mediator of androgen receptor expression and signaling.

Influence of Trichomonas vaginalis Macrophage Migration Inhibitory Factor on the Proliferation Activity of Prostate Epithelial Cell Line and Its Preliminary Mechanism

[andrology] The authors determined the influence of macrophage Trichomonas vaginalis macrophage migration inhibitory factor on prostate epithelial cells and its preliminary mechanism.

Combination Treatment of Docetaxel with Caffeic Acid Phenethyl Ester Suppresses the Survival and the Proliferation of Docetaxel-Resistant Prostate Cancer Cells via Induction of Apoptosis...

[Journal of Biomedical Science] Combination treatment of docetaxel with caffeic acid phenethyl ester effectively suppressed the proliferation and survival of docetaxel-resistant prostate cancer cells via inhibition of Bcl-2 and c-Myc as well as induction of metabolism interference.

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