prostate cancer

[Molecular Biology Reports] Investigators provided novel evidence that suggests a chief regulatory role for the TP73-TP73-AS1 axis in prostate cancer development and progression, suggesting that the TP73/TP73-AS1 axis can be a promising diagnostic and therapeutic target for prostate cancer.

[Asian Journal of andrology] Scientists demonstrated that mannose inhibited the proliferation and promoted the apoptosis of prostate cancer cells in vitro, and mannose was observed to have an anticancer effect in mice without harming their health.

[Clinical and Translational Oncology] The authors revealed ATG5-mediated autophagy was a key mechanism that controled the metastasis of prostate cancer by regulating p62 abundance and TWIST1 stabilization.

[Apoptosis] Researchers evaluated the combinatorial effect of HIC with abiraterone acetate targeted on androgen receptor on the inhibition of prostate cancer cells.

[Histology and Histopathology] Real-time quantitative PCR was used to detect the relative expression of fibroblast activation protein alpha mRNA in prostate cancer cell lines and human normal prostate epithelial cell line RWPE-1.

[Archiv Der Pharmazie] Scientists provided novel androgen receptor (AR)-directed proteolysis-targeting chimeras (PROTACs) and a clear rationale for further investigating AR involvement in lung cancer models.