prostate cancer

[Cancer Cell International] Researchers evaluated and confirmed the promising anti-tumor activity of olean-28,13β-lactam (B28) in vitro. RNA-seq profile indicated that multiple metabolic pathways were interrupted in B28 treated pancreatic adenocarcinoma cells.

[Cancer Science] Researchers observed that cell migration-inducing protein (CEMIP) upregulation facilitated ferroptosis resistance during ECM detachment by promoting cystine uptake in prostate cancer cells.

[Lantheus Holdings, Inc.] Lantheus Holdings, Inc. announced a strategic collaboration with Novartis to include PYLARIFY® in prostate cancer clinical trials with Pluvicto™.

[Communications Biology] The authors investigated integrative genomics using a patient-derived xenograft model recapitulating acquired, androgen receptor-dependent CRPC.

[British Journal of Cancer] Researchers investigated whether 5-aminolevulinic acid may increase the sensitisation of prostate cancer cells to radiotherapy through the generation of reactive oxygen species via its metabolite, protoporphyrin IX.

[Molecular Cancer Research] Vpr binding protein (VPRBP) knockdown in prostate cancer cells led to a significant decrease in cell proliferation, p53 stabilization, nucleolar fragmentation and increased p53 recruitment to the chromatin.