prostate cancer

[Scientific Reports] In vitro analyses confirmed association between overexpression of miR-17-5p and proliferation, migration and invasion in prostate cancer cell lines.

[Journal of Gene Medicine] Circular RNAs (circRNAs) are crucial regulators in tumor occurrence and progression, and circRNAs are enriched and stable in exosomes. Investigators explored the role and potential mechanism of cancer-derived exosomal circ_0081234 in prostate cancer.

[Scientific Reports] Through a kinome-centered CRISPR-Cas9 screen in CWR-R1 prostate cancer cells, scientists identified activated BRAF signaling as a determinant for enzalutamide resistance.

[Cancers] The authors discuss relatively understudied aspects of estrogen receptor-α and androgen receptor activity in regulating protein synthesis as well as the potential of targeting mRNA translation in breast and prostate cancer.

[Cell Death & Disease] Scientists reported that Family With Sequence Similarity 64 Member A (FAM64A) was up-regulated and positively associated with poor prognosis of patients with prostate cancer (PCa) by TCGA database and immunohistochemistry staining. Knockdown of FAM64A significantly suppressed the proliferation, migration, invasion, and cell cycle of PCa cells in vitro.

[Cancer Targeted Technology (Business Wire, Inc.)] Cancer Targeted Technology received a milestone payment from Advanced Accelerator Applications International S.A. triggered by the upcoming clinical trials of investigational 18F-CTT1057, a diagnostic PET imaging agent for prostate cancer.