prostate cells

[Journal of Antibiotics] From the natural product screening, the novel compound arabilin was isolated from Streptomyces sp. MK756-CF1. Unlike STK765173, arabilin could overcome resistance to enzalutamide.

[Biochemical and Biophysical Research Communications] The relevance of pleckstrin homology-like domain family A, member 3 (PHLDA3) in prostate cancer has not been explored. Scientists illustrated the possible roles and mechanisms of PHLDA3 in prostate cancer.

[Prostate] Scientists proposed that alterations in DNA damage response pathway contributed to taxane resistance, and identification of these alterations may provide a potential therapeutic target to resensitize docetaxel-refractory mCRPC to taxane-based therapy.

[Scientific Reports] The authors conjugated a Prostate-Specific Membrane Antigen (PSMA) inhibitor to the apoptosis-inducing human protease Granzyme B and the potent Pseudomonas exotoxin protein toxin fragment, PE35.

[Scientific Reports] Researchers investigated the role of Hedgehog-GLI signaling in sustaining androgen-independent growth of prostate cancer cells.

[Oncology Reports] Investigators investigated the inhibitory effect of miR‑367‑3p on the proliferation, invasion, and metastasis of prostate cancer cells.