SARS-CoV-2

[Genes & Diseases] With a predicted peptide library from SARS-CoV-2 S and N proteins, restricted to three of the most prominent HLA-A alleles in the Asian population, investigators found that specific CD8+ T cell responses were identified in over 75% of COVID-19 convalescent patients

[New England Journal of Medicine] A countrywide mass vaccination campaign with the use of an inactivated SARS-CoV-2 vaccine was conducted in Chile starting on February 2, 2021.

[EMBO Journal] Researchers conducted a comprehensive interactome study between the virus and host cells using tandem affinity purification and proximity labeling strategies and identified 437 human proteins as the high-confidence interacting proteins.

[PLOS Medicine] Antibody immunoreactivity against SARS-CoV-2 antigens and Spike variants, inhibition of Spike-driven virus–cell fusion, and infectious SARS-CoV-2 neutralization were characterized in 807 serial samples.

[Science Signaling] Scientists investigated the antiviral activities of long-chain polyPs against SARS-CoV-2 infection.

[Nature Communications] The authors used a yeast-display system to map all mutations to the viral spike receptor-binding domain (RBD) that escape binding by representatives of three potently neutralizing classes of anti-RBD antibodies with high-resolution structures.