stroke

[Science] Investigators profiled transcriptomes of 181,388 cells to define a cell atlas of the adult human cerebrovasculature, including endothelial cell molecular signatures with arteriovenous segmentation and expanded perivascular cell diversity.

[Current Stem Cell Research & Therapy] The authors explored the contribution of miRNAs in adipose-derived stem cell-extracellular vesicles to the treatment of cerebral ischemia.

[New England Journal of Medicine] Scientists review new types of clinical trials to evaluate whether cytoprotective drugs can slow infarct growth prior to reperfusion and/or ameliorate the consequences of reperfusion, such as haemorrhagic transformation.

[Translational Stroke Research] The authors provide a futher understanding of the therapeutic role of neural stem cells for ischemic stroke, and evaluate their prospects for future application in clinical patients of ischemic stroke.

[Stem Cell Reports] Neural progenitor cell (NPC) transplantation, combined with physical exercise, showed significant improvement in both structural and behavioral outcomes in stroke-damaged rats.

[Signal Transduction and Targeted Therapy] To screen the potential biomarkers of acute ischemic stroke (AIS) due to large vessel occlusion (LVO), proteomic analysis was performed to identify those distinct plasma protein profiles in AIS due to LVO with different collateral status.