Publication

[Molecular Therapy Oncology] CAR’TCR-T cells, co-expressing a CD33-CAR and a transgenic dNPM1-TCR, revealed increased and prolonged anti-tumor activity in vitro, particularly in case of low target antigen expression.

[Cell & Bioscience] The attenuated tumour targeting Salmonella typhimurium SL7207 strain was modified to carry chromosomally integrated shRNA expression cassettes at the xylA locus.

[Biofabrication] Human adipose-derived stem cells and human umbilical vein cells were prepared as spheroids, which were encapsulated in gelatin methacryloyl hydrogels to fabricate a 3D pre-vascularized tissue.

[PLOS One] In order to optimize the RNAi conditions for PVD neuron, scientists fed the worm strains with E. coli HT115 bacteria expressing dsRNA against mec-3, hpo-30, and tiam-1, whose loss of function were known to show dendrite morphology defects in PVD neuron.

[American Journal Of Sports Medicine] Overexpression of insulin-like growth factor 1 (IGF-1) via recombinant adeno-associated viral vectors would improve osteochondral repair and reduce parameters of early perifocal osteoarthrisis in sheep after six months in vivo.

[Molecular Pharmaceutics] Researchers systematically screened a range of nonviral vectors to identify optimal transfection conditions for mRNA delivery to MSCs.