Publication

[Cell Death & Disease] Researchers investigated the roles and mechanisms of Periostin in phenotypic transition of hepatic stellate cells and relevant abnormal cellular crosstalk during liver fibrosis.

[Nature Communications] Researchers presented a comprehensive analysis of more than 2 million SARS-CoV-2 raw read datasets submitted to the European COVID-19 Data Portal to identify co-infections and intra-host recombination.

[Nature Chemical Biology] Investigators demonstrated the generalizability of this approach with antigens from Ebola, SARS-CoV-2, and influenza viruses and observe enhanced neutralizing antibody responses in all cases.

[Nature Microbiology] Through a systematic evaluation of metabolite–drug–fungal interactions in the leading fungal meningitis pathogen, Cryptococcus neoformans, scientists found that brain glucose induces fungal tolerance to amphotericin B in mouse brain tissue and patient cerebrospinal fluid via the fungal glucose repression activator Mig1.

[Journal Of Clinical Investigation] Investigators conducted a clinical trial to assess the safety and efficacy of Plasmodium falciparum sporozoites Vaccine in HIV-positive individuals since the HIV infection status of participants in mass vaccination programs may be unknown.

[Cellular And Molecular Life Sciences] Researchers stimulated peripheral blood mononuclear cells from donors with and without diabetes with influenza A virus, anti-CD3/anti-CD28-coated beads, PMA and ionomycin, or an influenza viral peptide pool.