Publication

[PLOS Neglected Tropical Diseases] Researchers investigated the protective effects of excretory/secretory products from Schistosoma japonicum eggs on asthmatic inflammation. They established an allergic airway inflammation model in mice by alum-adjuvanted ovalbumin sensitization and challenge.

[Clinical And Experimental Pharmacology And Physiology] Investigators revealed the role of circ_0026579 in lipopolysaccharide-induced human lung fibroblast cell injury and the underlying mechanism.

[EMBO Molecular Medicine] Scientists used an epithelial-to-mesenchymal transition (EMT)-focused integrative functional genomic approach and identified an inverse association between short-chain fatty acids and EMT in NSCLC patients.

[Experimental & Molecular Medicine] Investigators demonstrated that the mRNA and protein levels of the class III histone deacetylase SIRT1 were upregulated by the kirsten rat sarcoma viral oncogene homologue (KRAS)Mut-Raf-MEK-c-Myc axis in KRASMut lung cancer cells and in lung tumors of a mouse model with spontaneous KrasG12D expression.

[Cell Death & Disease] Researchers reported that crotonylated brain expressed X-linked gene 2 (BEX2) plays an important role in inhibiting chemotherapeutic agent-induced apoptosis via enhancing mitophagy in human lung cancer cells.

[Scientific Reports] Scientists identified CSE1L as a novel inhibitor of the RBL2-DREAM pathway and target to activate RBL2-DREAM in NSCLC cells. CSE1L is an oncoprotein that maintains repression of genes that can be reactivated by HDAC inhibitors.