Publication

[Macromolecular Bioscience] Researchers leveraged a methacrylated hyaluronic acid hydrogel platform to study stromal cell mechanotransduction. Hydrogels were first formed through thiol-Michael addition to model normal soft tissue stiffness.

[Applied Biochemistry and Biotechnology] Investigators used proteomic analysis to explore the molecules that may contribute to the survival and proliferation of hypoxic preconditioned MSCs.

[Advanced Science] By single-cell RNA sequencing, bone marrow-derived MSCs were the most downregulated cell cluster, and coincidentally, Piezo1 expression was mostly enriched in those cells, and was substantially downregulated by unloading.

[Cancer Letters] The authors employed simultaneous two-step modifications to engineer MSCs and MSC-derived exosomes to create exosomes overexpressing the fused protein lysosome-associated membrane protein 2-interleukin 3 and hematopoietic cell E-selectin/L-selectin ligand.

[Cell Death Discovery] Researchers found that administration of antler stem cells improved the survival rate of pulmonary fibrosis mice and reduced lung fibrosis, collagen deposition, and myofibroblast differentiation.

[Phytotherapy Research] A diabetic cardiomyopathy mouse model was constructed, and the effects of ginsenoside RG1-induced MSCs on myocardial function and fibrosis in diabetic mice were evaluated.