Tag results:

Publication

PGD2/DP1 Axis Promotes Liver Regeneration by Secreting Wnt2 in Kupffer Cells in Mice

[Hepatology] Two-thirds partial hepatectomy, massive hepatectomy, and carbon tetrachloride-induced chronic injury were performed in mice to study the mechanisms of live regeneration.

Clinical Implications of Wnt Pathway Genetic Alterations in Men with Advanced Prostate Cancer

[Prostate Cancer and Prostatic Diseases] Investigators utilized the Prostate Cancer Precision Medicine Multi-Institutional Collaborative Effort clinical-genomic database for this retrospective analysis.

Targeting Valine Catabolism to Inhibit Metabolic Reprogramming in Prostate Cancer

[Cell Death & Disease] Through the suppression of branched-chain amino acid (BCAA) availability, researchers reported significantly reduced lipid content, strongly indicating that BCAAs were important lipogenic fuels in prostate cancer.

Embryonic Microenvironment Suppresses YY1 and YY1-Related Genes in Prostate Cancer Stem Cells

[Pathology - Research and Practice] To investigate the embryonic microenvironment impact on Yin yang 1 (YY1) expression in CSC populations, firstly cancer stem cells (CSCs) were microinjected into the inner cell mass of blastocysts and then prostate CSCs were co-cultured with blastocysts.

A Novel Prognostic Model of De Novo Metastatic Hormone-Sensitive Prostate Cancer to Optimize Treatment Intensity

[International Journal of Clinical Oncology] 1092 Japanese patients diagnosed with de novo metastatic hormone-sensitive prostate cancer between 2014 and 2020 were registered. The patients treated with androgen deprivation therapy and first-generation anti-androgens were assigned to the discovery or validation cohorts.

The PP2A Regulator IER5L Supports Prostate Cancer Progression

[Cell Death & Disease] The authors showed that the less studied member of the Immediate Early Response (IER) family, IER 5 like (IER5L), was upregulated in aggressive prostate cancer.

Popular