Publication

[Science Immunology] The authors used high-dimensional flow cytometry, transcriptomic analysis, functional assays, and precursor-product experiments to define the development pathway of Vγ9Vδ2 T cells in the postnatal thymus.

[Science Immunology] Investigators performed multiplexed single-cell analysis of intestinal and gluten-induced peripheral blood T cells from patients in different celiac disease states and healthy controls.

[Cell Reports Medicine] Scientists highlighted the pathophysiological importance of expanded CD8 T cell clones in the progression of acute graft-versus-host disease (GvHD) toward more severe clinical manifestations.

[Cancer Communications] The authors evaluated the role of ARID1A among a series of epigenetic modulators in TNBC and explored how low ARID1A expression contributed to adaptive immune resistance.

[OncoImmunology] Scientists identified an accumulation of tissue-resident lymphocytes including tissue-resident NK cells and CD8+ tissue-resident memory T cells toward the center of human non-small cell lung carcinomas.

[Journal of Immunology] Researchers showed that, in humans, granzyme K (GzmK) was predominantly expressed by innate-like lymphocytes, as well as a newly identified population of GzmK+CD8+ non– mucosal-associated invariant T cells with innate-like characteristics.