Publication

[Cell Stem Cell] Scientists found that early developmental spinal cord had higher levels of ECM proteins associated with neural development and axon growth, but fewer inhibitory proteoglycans, compared to those of adult spinal cord.

[Molecular Therapy] Investigators identified a long noncoding transcript, namely, lymphocyte-specific protein 1 pseudogene 5 (LSP1P5), that modulated ECM component deposition in keloids.

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Utilizing an optogenetic mitochondria-specific mechanostimulator, the authors revealed that mechanical tensile force drove tail-autotomy fission.

[Scientific Reports] Investigators employed 2-photon laser scanning microscopy to visualise the intrinsic second-harmonic generation signal emitted by collagen fibres in the heterogeneous ECM of human colon tumour tissues.

[Heliyon] Researchers investigated the effect of acacetin on hepatic stellate cell apoptosis, thereby improving hepatic fibrosis, and combined experimental validation and molecular docking to reveal the underlying mechanism.

[iScience] The authors showed that regulated adipose tissue (AT) regeneration in doxycycline-fed Tg-AT-hAGPAT2;mAgpat2-/- mice partially ameliorated hepatic steatosis at 12 weeks of age and caused reduced expression of genes involved in hepatic de novo lipogenesis despite partial AT regeneration compared to that in wild-type mice.