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Human Placental Mesenchymal Stem Cell-Derived Exosomes in Combination with Hyperbaric Oxygen Synergistically Promote Recovery after Spinal Cord Injury in Rats

[Neurotoxicity Research] Scientists investigated the combined effects of human placenta MSCs-derived exosomes along with hyperbaric oxygen in the recovery of spinal cord injury in rats.

Trichloroethylene Metabolite S-(1,2-Dichlorovinyl)-L-cysteine Stimulates Changes in Energy Metabolites and Amino Acids in the BeWo Human Placental Trophoblast Model during Syncytialization

[Chemical Research In Toxicology] Researchers investigated S-(1,2-dichlorovinyl)-l-cysteine-induced changes to energy metabolism and amino acids during forskolin-stimulated syncytialization in BeWo cells, a human villous trophoblastic cell line that modeled syncytialization in vitro.

Human Umbilical Cord Blood Mononuclear Cells Ameliorate Ischemic Brain Injury via Promoting Microglia/Macrophages M2 Polarization in MCAO Rats

[Experimental Brain Research] The authors explored whether human umbilical cord blood mononuclear cells treatment for cerebral infarction via regulation of microglia/macrophages polarization.

Characterization of Xenobiotic and Steroid Disposition Potential of Human Placental Tissue and Cell Lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by Quantitative Proteomics

[Drug Metabolism and Disposition] Investigators characterized the abundance of proteins involved in xenobiotic and steroid disposition in human placental tissue and compared the tissue proteomics data with four placental cell lines.

Directing iPSC Differentiation into iTenocytes Using Combined Scleraxis Overexpression and Cyclic Loading

[Journal Of Orthopaedic Research] The authors attempted to induce tenogenesis using stable Scleraxis (Scx) overexpression in combination with uniaxial mechanical stretch of iPSC-derived mesenchymal stromal-like cells.

Identification and Characterization of the Wilms Tumor Cancer Stem Cell

[Advanced Science] A nephrogenic progenitor cell with CSC characteristics driving Wilms tumor using spatial transcriptomics, bulk and single cell RNA sequencing, and complementary in vitro and transplantation experiments was identified and characterized.

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