Publication

[Breast Cancer Research] Investigators reported the development of an estrogen receptor-positive (ER+) breast tumor organoid medium that conserved ER expression, estrogen responsiveness, and dependence, as well as sensitivity to endocrine therapy of ER+ patient-derived xenograft organoids

[Nature Microbiology] Using cerebral organoids, organotypic culture of human brain explants from individuals without COVID-19 and post-mortem brain samples from individuals with COVID-19, investigators found that neural cells were permissive to SARS-CoV-2 to a low extent.

[The Journal of Physiology] To evaluate the impact of capillary versus sarcolemmal proximity, researchers compared the structure and function of skeletal muscle mitochondria located either lateral to embedded capillaries (PVM), adjacent to the sarcolemma but not in PVM pools or interspersed between sarcomeres.

[Journal of Cellular and Molecular Medicine] The tibial denervation model was used and the denervated tibia exhibited significantly lower mass as compared to sham operated bones.

[Molecular And Cellular Biochemistry] The authors investigated the expression of acyl-CoA synthetase long-chain family member 4 (ACSL4) in osteosarcoma (OS) tissues using immunohistochemistry staining staining of a human tissue microarray and in OS cells by qPCR assay.

[Blood Advances] Researchers showed that platelet endocytosis of fluorescent-labeled albumin, fibrinogen, and IgG was decreased in a patient and his daughter with familial platelet defect with predisposition to myeloid malignancy.