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LncRNA NEAT1 Protects Uremic Toxin-Induced Intestinal Epithelial Barrier Injury by Regulating mir-122-5p/Occludin Axis

[PLOS One] Human colon cancer cells were used to establish intestinal epithelial injury models with the urea treatment in different conditions.

The Anti-Diabetic PPARγ Agonist Pioglitazone Inhibits Cell Proliferation and Induces Metabolic Reprogramming in Prostate Cancer

[Molecular Cancer] The authors suggested that Pioglitazone reduces prostate cancer (PCa) cell proliferation and induces metabolic and epithelial changes, highlighting the potential of repurposing metabolic drugs for PCa therapy.

CASK Promotes Prostate Cancer Progression via Kinase-Dependent Activation of AKT

[International Journal of Biological Macromolecules] Researchers investigated the roles of calcium/calmodulin-dependent serine protein kinase in prostate cancer (PCa) progression, cell migration, and invasion. They found that CASK is up-regulated in PCa tissues of patients.

The PPARβ/CERK/C1P Signaling Pathway Is a Potential Mechanism by Which Antimony Exposure Promotes Prostate Cancer Cell Proliferation

[Ecotoxicology and Environmental Safety] To explore the relationship between antimony exposure and cell proliferation, scientists found that the level of ceramide-1-phosphate (C1P), one of the metabolites of ceramide, increased after antimony exposure, and C1P can promote the proliferation of prostate cancer cells and antagonize the apoptosis induced by ceramide.

Insights into the Cellular Lipid Cascade of Prostate Cells Explored Using Infrared Microspectroscopy

[Analyst] Fourier transform infrared imaging coupled with fluorescence microscopy was used to follow arachidonic acid metabolism in prostate cancer cell lines.

Sinularin Induces Autophagy-Dependent Cell Death by Activating ULK1 and Enhancing FOXO3-ATG4A Axis in Prostate Cancer Cells

[Scientific Reports] Scientists demonstrated that Sinularin triggers autophagy via two different mechanisms in prostate cancer cells.

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