Tag results:
Publication
Newsletters
Single-Cell RNA Sequencing Reveals Association of Aberrant Placental Trophoblasts and FN1 Reduction in Late-Onset Fetal Growth Restriction
[Placenta] Single-cell RNA sequencing was performed on the maternal side of placentas from two normal pregnant women and two pregnant women with FGR. Lentivirus transfection was used to establish a FN1 knockout model in trophoblast HTR-8-Svneo cells.
Intestinal Cell News
Prognostic Impact and Immunotherapeutic Implications of NETosis-Related Gene Signature in Gastric Cancer Patients
[Journal Of Cellular And Molecular Medicine] The authors explored the biological enrichment difference between high- and low-risk patients and found that many carcinogenic pathways were upregulated in the high-risk patients.
Hepatic Cell News
INO80-Dependent Remodeling of Transcriptional Regulatory Network Underlies the Progression of Heart Failure
[Circulation] The authors integrated human samples, genetic mouse models, and genomic approaches to identify the role of chromatin remodeling complex INO80 in heart homeostasis and dysfunction.
Hepatic Cell News
OTUD1 Promotes Isoprenaline- and Myocardial Infarction-Induced Heart Failure by Targeting PDE5A in Cardiomyocytes
[Biochimica Et Biophysica Acta-Molecular Basis Of Disease] Researchers investigated the role of the ovarian tumor deubiquitinase 1 (OTUD1) in isoprenaline- and myocardial infarction-induced heart failure and its molecular mechanism.
Hepatic Cell News
Predicting Myosin Heavy Chain Isoform from Post-Dissection Fiber Length in Human Skeletal Muscle Fibers
[American Journal Of Physiology-Cell Physiology] Researchers measured normalized fiber length, expressed as a % of length of the bundle from which the fiber was dissected, in single fibers immediately following dissection. 668 individual fibers were dissected from muscle tissue samples from healthy, young adults.
Hepatic Cell News
Myopathy-Causing Mutation R91P in the TPM3 Gene Drastically Impairs Structural and Functional Properties of Slow Skeletal Muscle Tropomyosin γβ-Heterodimer
[Archives of Biochemistry and Biophysics] The authors investigated the influence of the R91P mutation in the γ-chain on the properties of the γβ-tropomyosin heterodimer.