Publication

[Theranostics] Investigators developed a colon dual-targeting nanoparticle, for orally delivering bilirubin through hydrogel encapsulation of hyaluronic acid-modified poly (lactic-co-glycolic acid) nanoparticles.

[Prostate Cancer And Prostatic Diseases] Genomic classifiers provide a small but consistent improvement upon the prognostic ability of clinical classification schemes, which may be helpful when treatment decisions are uncertain.

[British Journal of Cancer] The impact of 2,4-dienoyl CoA reductase 2 (DECR2) and peroxisomal β-oxidation inhibition via thioridazine was examined in vitro, in vivo, and in clinical prostate tumours cultured ex vivo.

[Journal Of Experimental & Clinical Cancer Research] CCK8 assay and colony formation assay were used to illustrate the key role of AGPS in the progression of prostate cancer in vitro.

[Cancer Discovery] Researchers developed a targeted DNA methylation assay to detect castration-resistant neuroendocrine prostate cancer (CRPC-NE) using plasma cell-free DNA, which quantified tumor content and provided a phenotype evidence score that captured diverse CRPC phenotypes, leveraging regions to inform transcriptional state.

[Nature Communications] Scientists employed single-cell RNA sequencing to delineate molecular changes in tumor stroma that influence prostate cancer progression and metastasis.