Publication

[Cardiovascular Research] Contractility was measured of human induced pluripotent stem cell-derived cardiomyocytes harboring a hypertrophic cardiomyopathy mutation cultured in 2D and in 3D engineered heart tissue.

[Gastric Cancer] The effect of mind bomb 1 (MIB1) on peritoneal metastasis of gastric cancer was confirmed in vitro and in vivo. Co-immunoprecipitation and mass spectrometry demonstrated the association between MIB1 and DEAD-box helicase 3 X-linked (DDX3X).

[PeerJ] Single-cell RNA sequencing of CD45-negative cell fraction of breast cancer patients was performed. All circulating tumor cells were divided into nine groups according to their integrin profile.

[Journal of Experimental & Clinical Cancer Research] GFP-labeled tumor cells were sorted from invasive and non-invasive regions within co-cultures. Ui-RNA sequencing analysis was performed to find a gene cluster up-regulated in the invasive compartment.

[Translational Oncology] Bioinformatic analyses of The Cancer Genome Atlas data were performed, and the association of alkB homolog 5 (ALKBH5) in predicting overall survival in patients with intrahepatic cholangiocarcinoma was investigated.

[Breast Cancer Research] Ninety-seven patients with hormone receptor-positive metastatic breast cancer were prospectively enrolled during standard treatment at Samsung Medical Center.