Publication

[Hepatology Communications] Through in vivo CRISPR knockout screens targeting related E3 ligase genes in HCC nude mice models, investigators discovered Listerin (LTN1) as a novel tumor suppressor in HCC.

[Journal Of Biomolecular Structure & Dynamics] Pharmacophore-based virtual screening of a small molecule database was performed initially, and then the screened hits were docked to the active site of SIRT3 to choose the best binding modes.

[Scientific Reports] Investigators examined the ameliorative effects of camel milk and silymarin supplementation upon aflatoxin B1 induced hepatic injury in rats.

[Nutrition & Metabolism] Analysis using dot blot and epitranscriptomic chips revealed that the m6A modification pattern of the transcriptome in high-fat diet-induced fatty liver and free fatty acid-induced fatty hepatocytes showed significant changes.

[BMC Complementary Medicine And Therapies] Scientists evaluated the anti-proliferative effect of Bacillus coagulans MZY531 and apoptosis induction in the mouse H22 hepatocellular carcinoma cell line.

[Cancer Discovery] Using chromatin editing technology, scientists showed how such elements promote prostate cancer growth by regulating AR transcriptional activity.