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The Role of Regulatory B Cells in Immune Regulation and Childhood Allergic Asthma

[Molecular and Cellular Pediatrics] The authors discuss different human regulatory B cell (Bregs) subsets, several ways of Breg induction, as well as the mechanisms through which they exert immunoregulatory functions, and their role in childhood allergic asthma.

Advances in Targeting the Extracellular Matrix for Glaucoma Therapy: Current Updates

[Expert Opinion On Therapeutic Targets] The authors discuss the complex process of ECM regulation in trabecula meshwork (TM) and explore promising therapeutic targets. The role of transforming growthfFactor-β as a central player in ECM deposition in TM is discussed.

Redox and Metabolic Reprogramming in Breast Cancer and Cancer-Associated Adipose Tissue

[FEBS Letters] The authors provide an overview of the current knowledge of the redox profiles and regulation of intermediary metabolism in breast cancer while considering the tumor and cancer-associated adipose tissue of breast cancer as a unique Warburg's pseudo-organ.

Umbilical Cord-Derived Mesenchymal Stem Cell Secretome Promotes Skin Regeneration and Rejuvenation: From Mechanism to Therapeutics

[Cell Proliferation] The authors provide scientific support for the mechanistic investigation and clinical utilization of the umbilical cord-derived mesenchymal stem cell secretome in wound healing and skin rejuvenation.

Molecular Biomarkers in Prostate Cancer Tumorigenesis and Clinical Relevance

[Critical Reviews In Oncology Hematology] Scientists studied the molecular markers most associated with prostate cancer circulating tumor cells to better understand their function on tumorigenesis and metastatic cascade, the methodologies utilized to analyze these biomarkers, and their clinical significance.

Metabolic Interplay: Tumor Macrophages and Regulatory T Cells

[Trends In Cancer] The authors discuss how metabolites influence the immunosuppressive phenotypes of tumor-associated macrophages (TAMs) and Tregs, then describe how TAMs and Tregs, independently or collaboratively, utilize metabolic mechanisms to suppress the activity of CD8+ T cells.

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