Hydrophobic Tagging-Induced Degradation of PDEδ in Colon Cancer Cells

By
Justin.choi
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0
64
The first hydrophobic tagging-based PDEδ degraders were designed. Compound 17c efficiently bound to PDEδ and induced degradation of PDEδ in SW480 colon cancer cells.
[ACS Medicinal Chemistry Letters]

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AbstractGraphical Abstract