Parathyroid Hormone-Related Protein Promotes the Proliferation of Patient-Derived Glioblastoma Stem Cells via Activating cAMP/PKA Signaling Pathway

Using the Cancer Genome Atlas database, investigators found higher expression of PTHrP in GBM, which correlated inversely with survival. Glioblastoma stem cells were established from three human glioblastoma samples obtained after surgical resection.