NewslettersImmune Regulation NewsThe PTPN2/PTPN1 Inhibitor ABBV-CLS-484 Unleashes Potent Anti-Tumor ImmunityBy Laurisa Dohm - October 6, 20230255The authors showed that AC484 inflamed the tumor microenvironment and promoted natural killer cell and CD8+ T cell function by enhancing JAK–STAT signalling and reducing T cell dysfunction.[Nature]Full ArticlePress Release