Rewiring of the Epigenome and Chromatin Architecture by Exogenously Induced Retinoic Acid Signaling During Zebrafish Embryonic Development

Researchers stimulated the retinoic acid (RA) pathway by treating zebrafish embryos with all-trans-RA and used a combination of RNA-seq, ATAC-seq, ChIP-seq and HiChIP to gain insight into the molecular mechanisms by which exogenously induced RA signaling controlled gene expression.