NewslettersExtracellular Matrix News Spatial Single-Cell Protein Landscape Reveals Vimentinhigh Macrophages as Immune-Suppressive in the Microenvironment of Hepatocellular Carcinoma By Emily Salmini - September 27, 2024 0 379 Functional studies demonstrated that vimentin (VIMhigh) macrophages enhanced the immune-suppressive activity of regulatory T cells by mechanistically increasing the secretion of interleukin-1β. [Nature Cancer] Abstract