Identification of the Pro-Tumorigenic Role of the ELK4-METTL3-CEMIP Axis in Colorectal Carcinoma: Promotion of Cancer Cell Stemness and Malignant Phenotypes.

Scientists explored the specific role of CEMIP in the malignant phenotypes and stemness of colorectal cancer cells. CEMIP restoration reversed METTL3 knockdown-driven alterations in cell phenotypes and stemness.