Lung Adenocarcinoma-Derived IFN-γ Promotes Growth by Modulating CD8⁺ T Cell Production of CCR5 Chemokines

Researcher found that CD8⁺ T cells promote homing of CD4⁺Foxp3⁺ T regulatory cells to the tumor bed by increasing levels of CCR5 chemokines in the tumor microenvironment in an IFN-γ and TNF-α dependent manner.