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Vol. 17.21 – 05 November, 2026
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Scientists designed dynamic granular hydrogels that are modularly assembled using microgels with pre-programmed and precise degradation rates ranging from a few days to several weeks. [Advanced Materials]
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PUBLICATIONSListed by the impact factor of the journal
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Researchers investigated the role of nicotinamide N-methyltransferase in dermal fibroblast activation and fibrosis in systemic sclerosis.
[Annals of the Rheumatic Diseases]
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Investigators applied size-based fractionation to separate infusible decellularized ECM into its main components, enabling them to study how each component behaves in the context of inflammation and acute myocardial infarction.
[Advanced Science]
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Combining patient-derived ex vivo carboplatin screening with bulk and single-cell transcriptomics, functional perturbation in cancer-associated fibroblasts, and high-resolution spatial transcriptomics, scientists identified stromal apolipoprotein L4 (APOL4) as a biomarker of platinum sensitivity.
[Experimental & Molecular Medicine]
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The authors developed a xeno-free, spatially organized 3D synovial membrane model that reconstructs the structural relationship between the macrophage lining and fibroblast-rich sublining compartment. [Biofabrication]
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Investigators developed an RQK-based strategy for functional dental pulp regeneration by integrating ECM-like architecture with instructive bioactive cues in a self-assembling hydrogel system.
[Acta Biomaterialia]
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Researchers identified microtubules as a key component of the mechanotransduction machinery linking the mechanical microenvironment to Schlemm’s canal cell biomechanics and conventional outflow. [npj Biological Physics and Mechanics]
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The authors dissect the multifaceted roles of cancer-associated fibroblasts, from their promotion of cancer cell proliferation, invasion, and angiogenesis through secreted factors and extensive ECM remodeling, to their profound influence on the immune landscape. [Signal Transduction and Targeted Therapy]
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FibroBiologics, Inc. announced that the European Patent Office has granted European Patent No. EP 4454709, titled “Fibroblast Delivery of Tumor Inhibitory Agents. The patent covers methods of preparing fibroblasts as anti-cancer delivery compositions. [FibroBiologics, Inc.]
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Applied Biologics, LLC. announced the completion of enrollment into the sentinel safety cohort of its Phase III randomized controlled clinical trial evaluating BIOxHEALâ„¢ in patients with chronic, nonhealing diabetic foot ulcers.
[Applied Biologics, LLC. (BioSpace)]
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StimLabs announced the commercial launch of DermaForm, an FDA 510(k)-cleared porcine-derived particulate collagen scaffold that manages a range of acute and chronic wounds. [StimLabs]
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March 1-4, 2027 Keystone, Colorado, United States
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Baylor College of Medicine – Houston, Texas, United States
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University at Buffalo – Buffalo, New York, United States
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Baylor College of Medicine – Houston, Texas, United States
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The Icahn School of Medicine at Mount Sinai – New York City, New York, United States
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Human Technopole – Milan, Italy
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