Danielle Corrigan

[Communications Materials] The authors developed a technique to shrink-wrap micropatterned islands of corneal endothelial cells in a basement membrane-like layer of ECM that enabled the cells to maintain their cell-cell junctions and cytoskeletal structure while in suspension.

[npj Regenerative Medicine] Scientists combined the decellularized bovine tendon sheet (DBTS) with ECM from tendon-derived stem cells to fabricate a biomechanically and biochemically functional scaffold (tECM-DBTS), to provide a functional and stem cell ECM-based microenvironment for tendon regeneration.

[Bone Research] Utilizing a filamin B knockout mouse, researchers showed that the vertebral fusions in spondylocarpotarsal syndrome evolved from intervertebral disc degeneration and ossification of the annulus fibrosus, eventually leading to full trabecular bone formation.

[Current Biology] The authors survey the distribution, function, and formation of cytoplasmic bridges across the eukaryotic tree of life. They find that cytoplasmic bridges are widespread, and were likely ancestrally present, in almost all lineages of eukaryotes with clonal multicellularity

[Scientific Reports] The authors queried the expression of transglutaminase genes and examined whether they play a role in heart-associated immune responses.

[Cellular & Molecular Immunology] Using single-cell transcriptomic analysis, scientists found that several CD4+ T-cell subsets were present in the intestines of colitic mice, including an interferon (IFN)-γ-producing subset.