Jamie Kang

Mesenchymal Cell News

Apoptotic Bodies Derived from Human Umbilical Cord Mesenchymal Stem Cells Improve Recovery from Myocardial Infarction in Swine

[Autophagy] Researchers investigated the therapeutic effects of apoptotic bodies derived from human umbilical cord MSCs on cardiac recovery in a porcine model of myocardial infarction.

Mesenchymal Cell News

METTL3-m6a-STAT1/NF-κB Axis: A Key Switch for the Immunosuppressive Capacity of Mesenchymal Stem Cells

[Cellular & Molecular Biology Letters] This study established METTL3 as a critical regulator of the immunosuppressive capacity of MSCs, mediated through inducible nitric oxide synthase expression.

Mesenchymal Cell News

Synergistic Effects of Aligned PCL/rGO Scaffolds and Electrical Stimulation on BMSC Neuronal Differentiation

[Journal of Biomaterials Applications] A synergistic bio-electroactive platform was established to specifically induce neuronal differentiation from bone marrow MSCs by coupling spatially oriented, conductive polycaprolactone/reduced graphene oxide nanofibrous scaffolds with exogenous electrical stimulation.

Mesenchymal Cell News

Biomimetic Universal CAR-Mesenchymal Stem Cell Nanohybrids for Anti-Tumor Therapy

[Bioactive Materials] Investigators developed an innovative universal chimeric antigen receptor (CAR) nanoplatform by engineering MSCs with CAR and integrating them with multifunctional hybrid nanoparticles.

Mesenchymal Cell News

In Situ Electrospinning at the Operating Table to Immobilise Mesenchymal Stem Cells on the Bony Wall for the Regeneration of Osteoporotic Bone Defects

[Journal of Nanobiotechnology] MSCs were delivered into in vivo bone defects with a handheld electrospinning device as an improved cell seeding strategy.

Mesenchymal Cell News

Safety and Feasibility of Intravenous Fresh Adipose-Derived Mesenchymal Stem Cells in Secondary Progressive Multiple Sclerosis: Phase I/IIa Clinical Results

[Stem Cell Research & Therapy] High-dose fresh autologous adipose tissue-MSCs were intravenously administered to 10 female patients with secondary progressive multiple sclerosis in two doses, seven days apart.

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ANKRD1 Sustains a Neurogenic BMSC Niche and Counters Cognitive Aging

[International Journal of Oral Science] Researchers explored a neural crest-like progenitor niche in bone marrow MSCs with high neurogenic and proliferative capacity by single-cell transcriptomics.

Fusogenic Hybrid Gelled Nanovesicles Combining Mesenchymal Stromal Cell Cargo with Cholesterol-Modified Macrophage Membranes for Targeted Myocardial Infarction Therapy

[ACS Nano] Scientists developed a hybrid gelled nanovesicle, Hy-gNVs@chol, through chitosan-based protein enrichment and functional membrane replacement, enabling efficient concentration of MSC components to form gel nanoparticles while conferring inflammation-targeting capability.

Global Metabolomics Identifies New Extracellular Biomarkers of Nanovibration-Driven Mesenchymal Stem Cells Osteodifferentiation

[Biomaterials Advances] As part of an effort to eliminate synthetic osteogenic compounds, the authors characterized the metabolic adaptations of MSC to chemical-free nanovibration-induced osteodifferentiation.

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Jamie Kang

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