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Cell Therapy News

Human Umbilical Cord Blood Mesenchymal Stem Cells as a Potential Therapy for Schistosomal Hepatic Fibrosis: An Experimental Study

[Pathogens and Global Health] Researchers assessed the effect of human umbilical cord blood mesenchymal stem cells transplantation on schistosomal hepatic fibrosis in mice.

Cell Therapy News

Standardising the Histological Assessment of Late Post-Transplant Biopsies from Pediatric Liver Allograft Recipients

[Liver Transplantation] Whole slide digital images from 31 biopsies obtained ≥ 4 years post-transplant to determine eligibility for an immunosuppression withdrawal trial were selected to illustrate a range of typical histopathological findings seen in children with clinically stable grafts, including those associated with alloantibodies.

Cell Therapy News

TRIM31 Confers Protection against Nonalcoholic Steatohepatitis by Deactivating MAP3K7

[Hepatology] Scientists identified the RING-type E3 ubiquitin transferase-tripartite motif-containing protein 31, a member of E3 ubiquitin ligases family, as a novel and efficient endogenous inhibitor of transforming growth factor-beta-activated kinase 1.

Cell Therapy News

Magnetic Hydrogel for Cartilage Tissue Regeneration as Well as a Review on Advantages and Disadvantages of Different Cartilage Repair Strategies

[Biomed Research International] The authors illustrated various hydrogels used for cartilage regeneration by highlighting the magnetic hydrogels.

Cancer Stem Cell News

lncRNA KCNQ1OT1 Promotes EMT, Angiogenesis, and Stemness of Pituitary Adenoma by Upregulation of RAB11A

[Journal of Oncology] Scientists investigated the effect and mechanism of long noncoding RNA KCNQ1OT1 on pituitary adenoma. The KCNQ1OT1 expression in invasive and noninvasive PA tissues was detected by real-time fluorescence quantitative polymerase chain reaction.

Endothelial Cell News

Vascular Derived Endothelin Receptor a Controls Endothelin-Induced Retinal Ganglion Cell Death

[Cell Death Discovery] Scientists deleted Edn receptors from specific cell types to identify the critical endothelin receptor mediating retinal ganglion cell death in vivo.

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Sylvester Cancer Adding Cellular Therapy to its Arsenal against Metastatic Melanoma

[University of Miami Miller School of Medicine (EurekAlert!)] Patients in South Florida with metastatic melanoma will soon have access to tumor-infiltrating lymphocyte therapy, following its recent approval by the FDA. It will be available to patients at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

The Role of Yes Activated Protein (YAP) in Melanoma Metastasis

[iScience] The authors discuss how therapeutically targeting YAP through YAP inhibitors verteporfin and celastrol and its downstream mediators CCN1 and CCN2 might be useful in treating melanoma.

Exploration of the Photothermal Role of Curcumin-Loaded Targeted Carbon Nanotubes as a Potential Therapy for Melanoma Cancer

[Scientific Reports] Scientists designed and evaluated targeted carbon nanotubes containing curcumin, and assessed their in vitro cytotoxicity effects on melanoma cancer cells.

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